Intraspinal steroids: history, eYcacy, accidentality, and controversy with review of United States Food and Drug Administration reports
نویسندگان
چکیده
This review, covering a timespan of almost a century, attempts to answer five pressing questions: (1) Are intraspinal steroid therapies eVective for back pain or radicular syndromes? (2) Do epidural injections remain confined to the epidural space? (3) Are presently prescribed steroid formulations neurotoxic? (4) What are the risks of epidural steroid injection? (5) What information should be given to patients in obtaining informed consent for these procedures?
منابع مشابه
Intraspinal steroids: history, efficacy, accidentality, and controversy with review of United States Food and Drug Administration reports.
This review, covering a timespan of almost a century, attempts to answer five pressing questions: (1) Are intraspinal steroid therapies eVective for back pain or radicular syndromes? (2) Do epidural injections remain confined to the epidural space? (3) Are presently prescribed steroid formulations neurotoxic? (4) What are the risks of epidural steroid injection? (5) What information should be g...
متن کاملQuality Control of Non-Sterile Drug Product According to United States’ Pharmacopeia Instruction
Pharmaceutical products are classified into two groups according to the microbiological point of view: 1) sterile products and 2) non-sterile products. The sterilized term refers to the products that are free of any microorganisms, their production were done under aseptic conditions, but the production of non-sterile products were not under aseptic conditions; therefore, they are not free from ...
متن کاملA Comparative Study of Therapeutic Benefits of Intraspinal and Intravenous Bone Marrow Stromal Cell Administration to Spinal Cord Injuries
Background: Recent reports demonstrated that intravenous route as a minimally invasive method, similar to direct injection, is suitable for bone marrow stromal cell (BMSC) transplantation. In this study, we made a comparison of intraspinal and intravenous route of BMSC administration to repair injured spinal cord tissue. Methods: Six groups of adult female rats were used in this study. Laminect...
متن کاملSports supplements and Anabolic Androgenic Steroids
Recently, the use of sport supplements has become so common among most athletes. These supplements may contain undeclared substances that are banned by such international authorities as WHO, IOC and WADA. The present study, thus, is aimed at examining the final sport supplement products in terms of banned substances and measuring the adulteration level in order to prove the safety of these prod...
متن کاملReview of Natural History, Benefits and Risk Factors Pediatric Liver Transplantation
Liver or hepatic transplantation (LT) is the replacement of a diseased liver with part or whole healthy liver from another person (allograft). Human liver transplants were first performed by Thomas Starzl in the United States and Roy Calne in Cambridge, England in 1963 and 1967, respectively. Liver transplantation is a viable treatment option for end-stage liver disease and acute liver failure....
متن کامل